ABSTRACT
Burns during pregnancy poses a serious threat to the life of baby, as well as to the mother. More severely it is associated with various social and economical problems, as well as associated with illiteracy and poverty which many cases complicate its prevention. Burns during pregnancy influence maternal as well as foetal outcome. Keeping this in view a comprehensive task was undertaken to assess the maternal and foetal outcome in relation to burn extent and gestational age of foetus. A total of thirty two cases of burn females with pregnancy were analyzed. There were 23 maternal and 26 foetal deaths. Percentage of abortion during the third trimester was highest. Rate of maternal mortality increased with percentage of Total Body Surface Area (TBSA) burnt. Maximum incidence of maternal mortality rate was with cases of burns involving more than 50% TBSA.
Subject(s)
Burns/ethnology , Burns/mortality , Burns/pathology , Cause of Death , Coroners and Medical Examiners , Death Certificates , Female , Fetal Death/etiology , Fetal Development , Gestational Age , Humans , Maternal Death/etiology , Maternal Mortality/etiology , Pregnancy , Socioeconomic FactorsABSTRACT
Many natural drugs of Traditional Medicine have been shown to possess anti-oxidant activity. Unani Medicine, practised from Morocco to India, is likely to possess outstanding antioxidants. So, the Unani drug, Abresham [Silk Bombyx mori] Cocoon]. was studied for its effect on lipid Peroxidatior, [TBARS], SOD [Superoxide dismutase] and Catalase, The drug was also subjected to amino acid analysis, successive extraction etc. for physico-chemical characterization. After 7-day oral treatment with 175 mg/kg of 50% ethanolic extract of Abresham [Silk Cocoon] and Vit.E as the standard antioxidant for comparison, the rats: were subjected to immobilization stress and the post-mitochondrial supernatant of Iiver was used for estimating the team parameters. The MDA concentration was decreased and SOD and Catalase activity were increased not only vis a vis the untreutcd and Vit.E - treated stressed animals but even the unstressed animals [P<0.001]. So, the Unani drug Abresham [Silk Cocoon is shown to possess a striking antioxidant effect. The remarkable increase in both SOD and Catalase, that effectively block the generation of Reactive Oxygen Species [ROS] in two successive steps, indicates that the test drug's antioxidant effect is exerted mainly by ROS generation blockade